2-Butoxyethanol
2-Butoxyethanol is an organic compound with the chemical formula BuOC2H4OH (Bu = CH3CH2CH2CH2). This colorless liquid has a sweet, ether-like odor, as it derives from the family of glycol ethers, and is a butyl ether of ethylene glycol. As a relatively nonvolatile, inexpensive solvent, it is used in many domestic and industrial products because of its properties as a surfactant. It is a known respiratory irritant and can be acutely toxic, but animal studies did not find it to be mutagenic, and no studies suggest it is a human carcinogen. A study of 13 classroom air contaminants conducted in Portugal reported a statistically significant association with increased rates of nasal obstruction and a positive association below the level of statistical significance with a higher risk of obese asthma and increased child BMI.
| Names | |
|---|---|
| Preferred IUPAC name
2-Butoxyethanol | |
| Other names
2-Butoxyethanol Butyl cellosolve Butyl glycol Butyl monoether glycol EGBE (ethylene glycol monobutyl ether) Dowanol EB Eastman EB solvent 2-BE EGMBE Butyl oxitol Ektasolve EB Jeffersol EB | |
| Identifiers | |
3D model (JSmol) |
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| ChEBI | |
| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.003.550 |
| EC Number |
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PubChem CID |
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| RTECS number |
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| UNII | |
| UN number | 1993, 2810, 2369 |
CompTox Dashboard (EPA) |
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| Properties | |
| C6H14O2 | |
| Molar mass | 118.176 g·mol−1 |
| Appearance | Clear, colorless liquid |
| Density | 0.90 g/cm3, liquid |
| Melting point | −77 °C (−107 °F; 196 K) |
| Boiling point | 171 °C (340 °F; 444 K) |
| Miscible (and in most organic solvents) | |
| Vapor pressure | 0.8 mmHg |
| Acidity (pKa) | High pKa for −OH group |
Refractive index (nD) |
1.4198 (20 °C) |
| Viscosity | 2.9 cP at 25 °C (77 °F) |
| 2.08 D | |
| Hazards | |
| GHS labelling: | |
| Danger | |
| H227, H302, H311, H315, H319, H330, H336, H361, H370, H372 | |
| P201, P202, P210, P260, P261, P264, P270, P271, P280, P281, P284, P301+P312, P302+P352, P304+P340, P305+P351+P338, P307+P311, P308+P313, P310, P312, P314, P320, P321, P322, P330, P332+P313, P337+P313, P361, P362, P363, P370+P378, P403+P233, P403+P235, P405, P501 | |
| NFPA 704 (fire diamond) | |
| Flash point | 67 °C (153 °F; 340 K) |
| 245 °C (473 °F; 518 K) | |
| Explosive limits | 1.1–12.7% |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose) |
1230 mg/kg (mouse, oral) 470 mg/kg (rat, oral) 300 mg/kg (rabbit, oral) 1200 mg/kg (guinea pig, oral) 1480 mg/kg (rat, oral) |
LC50 (median concentration) |
450 ppm (rat, 4 hr) 700 ppm (mouse, 7 hr) |
| NIOSH (US health exposure limits): | |
PEL (Permissible) |
TWA 50 ppm (240 mg/m3) [skin] |
REL (Recommended) |
TWA 5 ppm (24 mg/m3) [skin] |
IDLH (Immediate danger) |
700 ppm |
| Safety data sheet (SDS) | |
| Related compounds | |
Related ethers |
2-Methoxyethanol 2-Ethoxyethanol |
Related compounds |
Ethylene glycol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references | |