1-Propanol
1-Propanol (also propan-1-ol, propanol, n-propyl alcohol) is a primary alcohol with the formula CH3CH2CH2OH and sometimes represented as PrOH or n-PrOH. It is a colourless liquid and an isomer of 2-propanol. It is formed naturally in small amounts during many fermentation processes and used as a solvent in the pharmaceutical industry, mainly for resins and cellulose esters, and, sometimes, as a disinfecting agent.
| Names | |
|---|---|
| Pronunciation | ˈprəʊpən.wən.ɒl |
| Preferred IUPAC name
Propan-1-ol | |
Other names
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| Identifiers | |
3D model (JSmol) |
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| 3DMet | |
| 1098242 | |
| ChEBI | |
| ChEMBL | |
| ChemSpider | |
| DrugBank | |
| ECHA InfoCard | 100.000.679 |
| EC Number |
|
| 25616 | |
| KEGG | |
| MeSH | 1-Propanol |
PubChem CID |
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| RTECS number |
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| UNII | |
| UN number | 1274 |
CompTox Dashboard (EPA) |
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| Properties | |
| C3H8O | |
| Molar mass | 60.096 g·mol−1 |
| Appearance | Colorless liquid |
| Odor | mild, alcohol-like |
| Density | 0.803 g/mL |
| Melting point | −126 °C; −195 °F; 147 K |
| Boiling point | 97 to 98 °C; 206 to 208 °F; 370 to 371 K |
| miscible | |
| log P | 0.329 |
| Vapor pressure | 1.99 kPa (at 20 °C) |
| Acidity (pKa) | 16 |
| Basicity (pKb) | −2 |
| −45.176·10−6 cm3/mol | |
Refractive index (nD) |
1.387 |
| Viscosity | 1.959 mPa·s (at 25 °C) |
| 1.68 D | |
| Thermochemistry | |
Heat capacity (C) |
143.96 J/(K·mol) |
Std molar entropy (S⦵298) |
192.8 J/(K·mol) |
Std enthalpy of formation (ΔfH⦵298) |
−302.79…−302.29 kJ/mol |
Std enthalpy of combustion (ΔcH⦵298) |
−2.02156…−2.02106 MJ/mol |
| Pharmacology | |
| D08AX03 (WHO) | |
| Hazards | |
| Occupational safety and health (OHS/OSH): | |
Main hazards |
Flammable liquid |
| GHS labelling: | |
| Danger | |
| H225, H302, H318, H336 | |
| P210, P261, P280, P305+P351+P338 | |
| NFPA 704 (fire diamond) | |
| Flash point | 22 °C (72 °F; 295 K) |
| 371 °C (700 °F; 644 K) | |
| Explosive limits | 2.2–13.7% |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose) |
2800 mg/kg (rabbit, oral) 1699 mg/kg (mouse, oral) 1870 mg/kg (rat, oral) |
| NIOSH (US health exposure limits): | |
PEL (Permissible) |
TWA 200 ppm (500 mg/m3) |
REL (Recommended) |
TWA 200 ppm (500 mg/m3) ST 250 ppm (625 mg/m3) [skin] |
IDLH (Immediate danger) |
800 ppm |
| Related compounds | |
Related compounds |
Propane Isopropyl alcohol Propanamine Ethanol Butanol |
| Supplementary data page | |
| 1-Propanol (data page) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references | |
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