β-Cyclodextrin

β-Cyclodextrin sometimes abbreviated as β-CD, is a heptasaccharide derived from glucose. The α- (alpha), β- (beta), and γ- (gamma) cyclodextrins correspond to six, seven, and eight glucose units, respectively. β-Cyclodextrin is the most used natural cyclodextrin in marketed medicines. The reason for this lies in the ease of its production and subsequent low price (more than 10,000 tons produced annually with an average bulk price of approximately 5 USD per kg).

β-Cyclodextrin
Names
IUPAC name
cyclomaltoheptaose
Systematic IUPAC name
cycloheptakis-(1→4)-α-D-glucopyranosyl
Other names
Cycloheptaamylose
Cycloheptadextrin
Cyclomaltoheptose
β-Cycloamylose
Schardinger β-Dextrin
betadex
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
DrugBank
ECHA InfoCard 100.028.631
EC Number
  • 233-007-4
E number E459 (thickeners, ...)
KEGG
UNII
  • C(C1C2C(C(C(O1)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)OC5C(OC(C(C5O)O)OC6C(OC(C(C6O)O)OC7C(OC(C(C7O)O)OC8C(OC(O2)C(C8O)O)CO)CO)CO)CO)CO)CO)O)O)O
Properties
C42H70O35
Molar mass 1134.987 g·mol−1
Appearance white solid
Melting point 501 °C (934 °F; 774 K) at fast heating rates, decomposition below 260 °C for conventional heating
18.5 g/L
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
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