Valsartan
Administration
- Type: Angiotensin II receptor antagonists
- Dosage Forms:
- Routes of Administration: oral
- Common Trade Names: Diovan
Adult Dosing
- 20-160mg PO 1-2 times per day
Pediatric Dosing
Safety/efficacy not established
Special Populations
- Pregnancy Rating: D
- Lactation risk: Infant risk cannot be ruled out
- Renal dosing: no adjustment
- Hepatic dosing: no adjustment
Contraindications
- Allergy to class/drug
- Concomitant aliskiren use in diabetic patients
Adverse Reactions
Serious
- Angioedema
- Acute renal failure
Common
- Hypotension
- Dizziness, headache
- Elevated BUN/Cr
- Cough
Pharmacology
- Half-life: 6h
- Metabolism:
- Excretion: Mostly fecal
Mechanism of Action
- Angiotensin II antagonist
References
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