Roseola infantum
Background
- Also known as Exanthem Subitum
- Likely caused by HHV-6
Clinical Features
Roseola on a 21-month-old girl
- 3-5d prodrome of high fever → then defervescence → then rash for 1-2d
- Rash - erythematous macular eruption of discrete, pink lesions
- Mostly on neck, trunk, buttocks
- No mucus membrane involvement
- Lymphadenopathy often present
- Often erythematous tympanic membranes
- May have sterile pyuria
Complications
- Seizures
- Aseptic meningitis
- Encephalitis
- Thrombocytopenic purpura
Differential Diagnosis
Pediatric Rash
- Atopic dermatitis
- Bed bugs
- Contact dermatitis
- Drug rash
- Erythema Infectiosum (Fifth disease)
- Hand-foot-and-mouth disease
- Henoch-Schonlein Purpura (HSP)
- Herpangina
- Herpes simplex virus
- Infectious Mononucleosis
- Meningitis
- Measles
- Molluscum contagiosum
- Roseola infantum
- Rubella German measles)
- Scabies
- Scarlet fever
- Smallpox
- Varicella (Chickenpox)
Evaluation
- Clinical diagnosis, based on history and physical exam
Management
- Supportive care
Disposition
- Discharge
See Also
- Pediatric Rashes
References
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