Acrodermatitis enteropathica
Background
- Disorder of zinc metabolism (either congenital mutation, abnormal zinc characteristics in mother's breast milk, or due to surgery affecting upper GI tract) that leads to effective zinc deficiency
Clinical Features
- Diarrhea, steatorrhea
- Irritation/inflammation of skin around body openings (e.g. mouth, anus, eyes, hands/feet)
- Typically vesiculobullous initially, then dry and resemble psoriasis rash
- Nails may become abnormal
- Alopecia
- Conjunctivitis
Differential Diagnosis
Evaluation
- Serum zinc level typically low
Management
- Zinc sulfate supplementation
Disposition
See Also
External Links
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