Questions tagged [drc]

Analysis of Dose-Response Curves.

Analysis of dose-response data is made available through a suite of flexible and versatile model fitting and after-fitting functions.

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Interpolations misalign with plotted curve from which they are derived from (drc package)

I am trying to determine the amount of protein (TIMP) against a four-parametric curve of od (optical density) vs. TIMP. The issue here lies in that when I plot the interpolations on top of the same standard curve from which they were derived from…
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How to add ED function output from the console to a DRM plot

Within the DRC Package, I am trying to add the output that I get from running the ED function into a text box that I have placed on my DRM plot. Any ideas on how to write the script so that I can include the ED function in the text function and…
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Bioassay dose response fitting with heteroscedastic data

I am using the drc package in R to fit dose response curves (4-param logistic: LL.4) for biological assays. The data I collect is typically heteroscedastic (example image below). I am looking for ways to account for this when calling drm. I have…
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Fitting a constrained dose-response log-logistic curve

I have dose-response data I'd like to fit a log-logistic curve for. Here's the data: df <-…
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Displaying Axis Percentages in ggplot2 without: `scale_y_continuous(labels=percent)`

I would like to display percents on the Y-Axis. It appears the most common method of doing this is in ggplot2 is via scales: scale_y_continuous(labels=percent). I am unable to use this method because I am implementing labels=every_nth, a custom…
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Adding horizontal lines to log transformed axes in ggplot2

I want to add horizontal and vertical lines to my plot which has a log-transformed x-axis. If I cut the code, before the 'axes' transformation, everything plots as expected (code below). #image: SOLVED - HERE . I had searched the stack but a…
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ggplot2 only plotting last variable from grouped dataframe

I am trying to plot 3 models with group=model, but only the last model in the data.frame is being plotted. I've done a fair amount of searching online but haven't been able to figure out what the problem is. The data.frame has 3 columns: dose(x…
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Dose Response Curves - odd ED50 values with drc

I am trying to plot a dose response curve using drc. I've got two cell lines (gr, ctrl) and I am trying to figure out the ED50 for both of them in the same plot. The Cells are treated with the same drug, confluence beeing the meassured…
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